- authorisedTherapeutic use (Phase IV)
Acetazolamide in combination with SGLT2i in patients with volume overload and acute heart failure
This study looks at a new way to treat acute heart failure, a condition where your heart struggles to pump enough blood. It combines existing heart medications (Jardiance, Forxiga) with another drug (Diamox) to see if this helps the body get rid of extra salt and water, which can build up during heart failure.
Belgium - recruitingPHASE3
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
This study is testing a new drug called finerenone for people hospitalised with heart failure. We want to see if it's safe and effective for patients whose hearts can still pump blood fairly well, to improve their health and quality of life.
United States · Argentina · Australia - ongoing, recruitingPhase III and phase IV (Integrated)
A Multicenter, Randomized, Double-Blind, Parallel Group, Placebo-Controlled Trial to Evaluate the Effect of In-Hospital Initiation of Dapagliflozin on Clinical Outcomes in Patients Who Have Been Stabilized During Hospitalization for Acute Heart Failure
This study looks at whether a medicine called dapagliflozin, started in hospital, can help patients who have been treated for sudden heart failure. It aims to see if the medicine can prevent future heart problems or hospital stays.
Poland · Hungary · Czechia - active not recruiting
Prospective Validation of the CoDE-HF Algorithm for the Diagnosis of Acute Heart Failure
This study is testing a new computer tool called CoDE-HF that helps doctors quickly diagnose acute heart failure. This condition means your heart suddenly can't pump blood well. The tool combines a blood test result with patient information to help get the right diagnosis faster.
United Kingdom - recruitingNA
Acute Heart Failure With Reduced Ejection Fraction - COngestion Discharge Evaluation
This study looks at people with a type of heart failure called 'heart failure with reduced ejection fraction' who are in hospital. Researchers want to find early signs of problems, like swelling, to help prevent them from needing to come back to the hospital soon after discharge.
France - recruiting
MRI Assessment of Pulmonary Edema in Acute Heart Failure
This study uses MRI scans to get a clearer picture of how much fluid is in the lungs of people with sudden heart failure. Researchers want to see how this fluid changes during hospital stay and if these measurements can predict future health risks.
Canada