- recruiting
Visual Frailty in Ageing
This study looks at 'visual frailty' in older people with a common eye condition called AMD. Researchers want to understand and measure how vision problems, general health, and mental well-being are linked, to help improve care for ageing eyes.
United Kingdom - recruitingNA
Post-market Clinical Investigation of the SING IMT System, Model NG SI IMT 3X in Patients With End-stage Age-related Macular Degeneration
This study looks at a tiny telescope implant (SING IMT) for people with severe age-related macular degeneration (AMD). It aims to see if the implant is safe and helps improve blurry central vision, with patients receiving follow-up care and vision training for 12 months.
Belgium · France · Germany - recruiting
Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression
This study looks at how a specific type of age-related macular degeneration (AMD) progresses. It uses AI and eye scans to understand changes over two years, aiming to personalize future monitoring for people with this AMD.
Austria · France · Slovenia - active not recruiting
Retinal Pigment Epithelium Safety Study for Patients in B4711001
This study is checking on the long-term safety of a treatment for macular degeneration, called PF-05206388. It follows patients who were part of an earlier study (B4711001) for another four years to make sure they are doing well.
United Kingdom - ongoing, recruitingTherapeutic exploratory (Phase II)
Molecular imaging exploration of ocular angiogenic activity and evaluation of its value in therapeutic follow-up of AMD patients
This study looks at a new scanning method to see how much activity there is in the eyes of people with a common eye condition called Age-related Macular Degeneration (AMD). We want to see if this scan can help doctors understand how well treatments are working.
France - recruitingNA
Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration
This study is looking at a new treatment called i-Lumen AMD, which uses a gentle electric current to help people with a common eye condition called Age-related Macular Degeneration (AMD). The aim is to see if it's safe and effective for slowing down the problem in the eyes.
United States · Australia · New Zealand - recruitingNA
Photobiomodulation in Dry Age Related Macular Degeneration
This study is looking at whether yellow and red light treatment can help people with dry age-related macular degeneration (AMD). Researchers want to see if this light therapy can reduce deposits in the eye and improve vision. Participants will either receive the light treatment or a dummy treatment.
France · Italy · Turkey (Türkiye) - recruiting
Personalised Monitoring of Early and Intermediate Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression
This study uses AI to better understand and predict how Age-Related Macular Degeneration (AMD) progresses. We want to find out why some people with early AMD develop advanced vision loss over two years and how to spot it sooner using eye scans.
Austria · France · Slovenia - active not recruiting
Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - PINNACLE
This study, called PINNACLE, looks into early changes in Age-related Macular Degeneration (AMD) before it gets worse. Researchers will track patients' eyes using special scans to understand how the disease develops. This helps scientists learn more, potentially leading to better ways to help people with AMD.
Austria · Switzerland · United Kingdom - recruitingPHASE2, PHASE3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
This study is looking for better treatments for a common eye condition called wet macular degeneration. Researchers want to see if a new medicine, tiespectus, works as well as an existing treatment, aflibercept. It's for people recently diagnosed with this condition.
United States · Argentina · Australia - recruiting
Functional and Anatomical Visual Investigations in Patients With Early Forms of Age-related Macular Degeneration
This study looks at people with early signs of Age-related Macular Degeneration (AMD) to understand how their vision is affected. Researchers want to find new ways to spot the disease early and slow it down before it gets worse.
France - recruiting
Dark adaptation and Retinal Topography in AMD (DART-AMD)
This study looks at how people with early AMD adapt to darkness and how their eye changes affect this. It aims to improve tests for new treatments that slow down AMD progression and is for people aged 55-85 with intermediate AMD.
United Kingdom · England - enrolling by invitation
Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - SUMMIT (Part 2)
This study, SUMMIT, is a continuation of the PINNACLE study. It's for people with a common eye condition called Age-related Macular Degeneration (AMD) to understand how it progresses over time. We're looking for early changes that lead to advanced AMD.
Austria · United Kingdom - recruitingNA
Survival of Monocytes Collected From Patients With Atrophic AMD in Retinal Pigmented Epithelium Explants
This study looks at how immune cells (monocytes) from people with a type of age-related macular degeneration (AMD) called atrophic AMD survive on eye cells. We want to understand if these cells behave differently, as this could help find new treatments for this condition, which currently has no cure.
France - active not recruitingPHASE2
A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration
This study is testing a new medicine, Iptacopan, to see if it can stop or slow down age-related macular degeneration (AMD). Researchers are looking at people with early or intermediate AMD in one eye and a more advanced type in the other eye.
United States · China · Puerto Rico