- recruiting
CMR Right Ventricular Contractile Reserve Following Lung Resection
This study looks at how lung surgery affects heart health. We're using special heart scans to see if removing part of a lung changes how the heart's right side works, and if this affects how well people can do daily activities.
United Kingdom - not yet recruiting
Cognitive Assessment And Post-Operative Complications After Surgery: Linking Anaesthesia And Risk
This study looks at confusion and memory problems some older people experience after surgery. We're testing how best to study these issues and see if memory tests and blood samples can help us understand why they happen, aiming to make surgery safer for the brain.
United Kingdom - enrolling by invitation
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
This study looks at different ways to give pain relief during labour (epidural, DPE, CSE) and how well they work if a C-section is needed. It aims to see if newer methods make it easier to use the same pain relief for surgery.
United States · Canada - recruitingNA
Evaluation of the Impact of Virtual Reality on Sedation Use in Patients Undergoing Regional Anesthesia for Scheduled Orthopedic Surgery
This study looks at whether using virtual reality (VR) alongside simple relaxation techniques can help reduce anxiety during orthopaedic surgery where you're awake but numb. Researchers want to see if VR makes patients feel calmer and more satisfied than standard care.
France - recruitingPHASE2
Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery
This study looks at whether a medicine called Aprepitant can stop children from feeling sick and throwing up after surgery for a curved spine. It compares Aprepitant to a dummy pill to see if it helps.
Canada - recruiting
Classification and Prediction of Difficult Awake Tracheal Intubation With Flexible Bronchoscopes
This study looks at making a better way to predict and classify difficult awake intubations using a thin, flexible tube called a bronchoscope. This helps doctors prepare better when someone needs help breathing during a medical procedure, aiming to make it safer and smoother.
Germany - recruitingPHASE3
Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia
This study looks at whether calming medicines given before surgery help children aged 7-18 feel better. Researchers want to see if these medicines, Midazolam or Dexmedetomidine, reduce anxiety without causing new problems after an operation.
France - active not recruitingPHASE4
Perioperative UtiLisation of SupplEmental Oxygen
This study looks at how much oxygen patients need during surgery. Some experts suggest high oxygen levels, but new evidence hints that less might be safer. Researchers want to find the best amount of oxygen to give during operations to help patients recover well.
United Kingdom - not yet recruiting
Anaesthetic Technique for Minor Lower Limb Amputation Surgery (ATLLAS)
This study looks at different types of anaesthesia used for operations to remove part of the leg below the ankle. Specifically, it compares local nerve blocks with general anaesthesia to see which is safer and leads to a quicker recovery for patients.
United Kingdom - recruitingNA
Anesthesia Induced Brain Cancer Survival (ABC Survival): A Feasibility Study
This study looks at how different types of anaesthesia might affect brain cancer survival, especially for aggressive types. It compares propofol (given through a drip) with sevoflurane (a gas) during surgery for brain tumours, to see if one helps patients live longer.
Canada - recruiting
Fasting Induced Hypoglycaemia in Anaesthetised Paediatric Patients
This study looks into low blood sugar (hypoglycemia) in children having surgery under general anaesthetic. It aims to understand why some children develop low blood sugar during fasting and how best to prevent and treat it, especially in younger children.
United Kingdom - recruitingNA
Open Lung Protective Extubation Following General Anesthesia
This study looks at different ways to help your lungs after an operation under general anaesthetic. It compares a special “open-lung” technique with the usual way, to see if it reduces problems like lung collapse for patients having abdominal surgery.
Canada - recruitingNA
Neurocognitive Disorders After Major Surgery in Elderly
This study looks at whether a special way of giving anaesthesia to people over 70 during major surgery can reduce memory and thinking problems afterwards. It compares a brain-wave guided method with standard care.
Canada - not yet recruiting
Prospective Validation of Intraoperative Blood Pressure Monitors
This study looks at how well different blood pressure monitors work during operations. It compares regular cuff measurements with more invasive methods to see if they give the same readings in patients having surgery under general anaesthetic. The aim is to understand the differences better.
Canada - recruitingPHASE4
Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception.
This study looks at whether a heart medication called esmolol can help reduce pain meds during and after surgery. It combines esmolol with special monitoring to see if it makes a difference for patients having certain abdominal surgeries.
Canada - recruiting
Prediction of Propofol Effect-Site Concentration Associated With Deep Anesthesia
This study looks at how much propofol anaesthetic people need to reach a deep sleep during an operation. Researchers want to see if brain activity and thinking skills before surgery can predict the right dose for each person.
Canada - recruitingPHASE2
Intravenous Dexmedetomidine as an Adjuvant to Locoregional Anesthesia in Pediatric Surgery
This study looks at whether a medicine called dexmedetomidine, given during surgery, can help reduce pain after operations in children aged 1 to 7. It aims to see if it helps with pain, reduces the need for strong painkillers, and improves recovery.
France - not yet recruitingNA
Pre-anesthetic Teleconsultations During Pregnancy
This study looks at how good and helpful online doctor's appointments (teleconsultations) are for pregnant people compared to in-person visits, before they give birth. We want to see if online appointments are just as good at making sure everything is safe for anaesthesia.
France - recruitingPHASE2, PHASE3
Bupivacaine and Epinephrine Injection Study
This study looks at a common nose operation for sinus problems. Researchers want to see if a special injection during surgery helps doctors see better and reduces bleeding, compared to having no injection at all. It's for adults aged 19 and over.
Canada - recruitingNA
Apnoeic Oxygenation During Pediatric Tracheal Intubation
This study looks at whether giving extra oxygen through a thin tube during a child's anaesthetic helps keep their oxygen levels up. It aims to make anaesthesia safer for children aged up to 6 years old undergoing surgery, specifically reducing problems with low oxygen.
Germany