- recruiting
Visual Frailty in Ageing
This study looks at 'visual frailty' in older people with a common eye condition called AMD. Researchers want to understand and measure how vision problems, general health, and mental well-being are linked, to help improve care for ageing eyes.
United Kingdom - recruiting
CBT and the Neural Circuits of Anxiety
This study looks at how a talking therapy called CBT changes the brain in people with anxiety. It aims to understand why CBT works, hoping to make treatments even better and more personal for anxiety in the future.
United Kingdom - recruitingNA
Effectiveness of CAT-GSH for Returning Patients
This study looks at two types of guided self-help therapy for people who have had anxiety or low mood before and are returning to NHS Talking Therapies. It compares CAT-GSH with CBT-GSH to see which works best and is preferred for those coming back for more support.
United Kingdom - not yet recruiting
Symptoms of Anxiety and/or Depression and SDM in Older Patients With CLTI
This study looks at how anxiety and depression affect older people with a serious leg condition (CLTI) and their surgery outcomes. It explores how doctors can work with patients to make important healthcare decisions.
United Kingdom - recruitingNA
The Effects of High-dose Vitamin B6 on Depression and Anxiety Symptoms
This study looks at whether high doses of Vitamin B6 can help reduce feelings of anxiety and depression. Researchers want to see if it changes brain activity and improves symptoms in people aged 18-41.
United Kingdom - recruitingNA
Virtual Reality in Elective Caesarean Births Study (VREC)
This study looks at whether watching a special virtual reality film can help reduce anxiety for women having an planned C-section at Royal United Hospital. It compares this film to the usual information given to see if it makes a difference.
United Kingdom - recruitingNA
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
This study looks at whether a special nutritional drink, 'Think Tank', can help middle-aged women aged 40-60 think more clearly after stressful experiences. Researchers will compare it to a dummy drink to see if it improves memory, attention, and overall well-being.
United Kingdom - active not recruitingNA
Fibre and Mental Wellbeing Feasibility Trial
This study looks at whether eating an extra 10 grams of fibre daily for two weeks can improve how young adults aged 18-40 feel mentally. It focuses on sleep, anxiety, and stress to see if diet changes can boost well-being.
United Kingdom - recruiting
Real-World Evidence in Patient-Reported Outcomes for Medical Cannabis (MC-RWE)
This study looks at how medical cannabis helps people in the UK with pain, sleep problems, anxiety, depression, or epilepsy. We want to see how well it works over time using patient feedback.
Canada - recruitingNA
Internet-delivered Cognitive Behaviour Therapy for Students: Duration Preference Trial
This study looks at online mental health courses for university and college students dealing with depression or anxiety. It compares different course lengths (fast, 5-week, or 8-week options) to see which ones students prefer and find most helpful for managing their feelings.
Canada - recruitingNA
Internet-Delivered Cognitive Behaviour Therapy for Depression and Anxiety in Perinatal Parents
This study looks at an online therapy program for new and expecting parents feeling anxious or down. It checks how well this program, called the Wellbeing Course for New and Expecting Parents, helps parents and if it's easy to use. The program lasts 8 weeks.
Canada - active not recruitingNA
CAMH PARTNERs Integrated Care Study
This study looks at a new way to help people with depression, anxiety, or alcohol issues. It uses a special team and phone support to work with your family doctor. We want to see if this helps you feel better and improves your quality of life.
Canada - recruitingNA
In Vivo Exposure vs. Videochat-Based Vicarious Exposure
This study looks at new ways to help people with spider phobia. It compares traditional exposure therapy, where you face your fear directly, with a new video-based method. We want to see how well these work to reduce fear and disgust.
Germany - not yet recruitingNA
SPAMLO-3.0 : Having Fun Shedding Light on Darkness, a Playful Approach to Reduce Anxiety in Palliative Care
This study is testing if a computer game called SPAMLO can help reduce anxiety for people in palliative (end-of-life) care. It aims to make information about palliative care easier to understand in a fun way.
France - recruitingNA
Trial of an Online Group Psychotherapy Intervention for Common Mental Health Disorders
This study tests an online group therapy for common mental health problems like anxiety and depression. It checks if changing the therapy module order helps, if certain modules suit different people, and how it compares to standard care like individual therapy.
United Kingdom - recruiting
Climate Anxiety in a Young Population at Risk of Suicide
This study looks at how worries about climate change affect the mental health of young people, aged 16-24, who are already seeing a doctor for mental health concerns. Researchers want to see if there's a link between climate anxiety and thoughts about suicide.
France - recruiting
Randomized, Single-blind Pilot Study Assessing the Effect of Cutaneous RESonance Stimulation SYMPAthetic and Parasympathetic Tone and Anxiety in Patients Admitted for Cardiac Surgery
This study is looking at a gentle skin stimulation technique (RESC) to help reduce anxiety in people having heart surgery. Researchers want to see if it can balance the body's stress response and make patients feel calmer before their operation.
France - recruitingNA
Ecological Momentary Intervention for Reward in Anhedonia
This study looks at a new way to help people with anhedonia (finding less pleasure in things), anxiety, and depression. It uses a smartphone app over two weeks to teach skills like positive thinking and managing stress.
Germany - recruitingNA
Transdiagnostic Internet Cognitive-behavior Therapy for Mixed Anxiety and Depressive Symptoms in Postnatal Women
This study looks at an online therapy program for new mothers in France and Canada who are feeling anxious or down after giving birth. It aims to see if adding this online help to their usual care works better than usual care alone to improve their mood.
Canada - active not recruitingNA
Virtual Reality to Reduce Pre-procedure Anxiety Prior ECT
This study explores if virtual reality (VR) videos can help reduce anxiety in patients before electroconvulsive therapy (ECT). It compares VR education to standard discussions, measuring anxiety, knowledge, heart rate, and blood pressure to see which method works best.
Canada - recruitingNA
Effects of Feel Free® Classic Tonic on Stress and Pharmacokinetics in Healthy Adults
This study looks at how a tonic called Feel Free® Classic affects stress in healthy adults. Researchers want to see if it reduces feelings of stress and how the body handles its ingredients, kava and kratom.
Canada - not yet recruiting
Global Survey on Newborns' HOspitalisation and Parental Experiences - the HOPE Study
This study is a worldwide survey for parents whose newborns needed special hospital care. It looks at their experiences and feelings, especially focusing on support systems and how hospitals care for families.
Germany - recruitingNA
Measurement of the Hippocampal Theta Rhythm From the Outer Ear Canal
This study explores a new, non-invasive way to measure brain activity linked to anxiety directly from your ear. We are testing if special ear sensors can detect a specific brain rhythm (theta) that changes when people are anxious, potentially leading to better anxiety diagnosis.
Canada - recruitingNA
Evaluating and Implementing The CONNECT Program - a Group-Based Telehealth Intervention to Reduce Social Isolation, Loneliness, and Mental Health Symptoms in Adults Ages 55+, Compared to Routine Community-Based Programming
This study looks at The CONNECT Program, a virtual group activity for adults over 55. It aims to reduce feelings of loneliness, isolation, anxiety, and depression by helping people connect and learn new coping skills, comparing it to usual community activities.
Canada - recruitingNA
Efficacy on Anxiety of the Digital Music Application Versus Equimolar Mixture of Oxygen and Nitrous Oxide in Patients Receiving CT-guided Lumbar Infiltration
This study looks at using a digital music app to help people with back pain feel less anxious during CT scans. It compares music to a gas mix (nitrous oxide and oxygen) currently used, hoping music works just as well but is easier and more comfortable.
France - recruitingNA
Effect of Virtual Reality Use on Preoperative Anxiety
This study looks at whether using special virtual reality (VR) glasses can help reduce anxiety in adults before their planned surgery. Researchers will compare those who use VR with those who don't, to see if it makes a difference to their worry, stress, and pain.
Germany - recruiting
Eco-anxiety and Suicide
This study looks at the link between worry about climate change (eco-anxiety) and suicide risk in teenagers aged 12-16. It aims to understand if eco-anxiety makes some young people more vulnerable to suicidal thoughts or actions, helping us better support them.
France - recruitingNA
APA and Relaxation by Biofeedback in Patients With Haematological Malignancy Admitted in ICU
This study looks at how exercise and relaxation can help reduce anxiety for people with blood cancer in intensive care. It explores different types of exercise and relaxation, including special games and a technique called biofeedback, to see which works best.
France - recruitingNA
Music Intervention in Chronic Pain Patients
This study looks at whether listening to music can help people who live with ongoing pain. Researchers want to see if personalised music sessions can reduce pain, anxiety, and make people feel better overall, compared to not having music sessions.
Canada - not yet recruitingNA
Responsive Nature-Driven Imagery to Reduce Delirium After Cardiac Surgery
This study is testing a new device called MindfulGarden for people having heart surgery. It uses calming nature pictures to help reduce confusion, worry, and agitation after the operation. Researchers want to see if it makes recovery better and reduces the need for certain medications.
Canada - recruitingNA
Internet-Delivered Cognitive Behaviour Therapy for Women with Perimenopausal Anxiety
This study looks at an online therapy program for women aged 40-60 who are going through perimenopause and have anxiety. It wants to see if this online support can help reduce their anxiety symptoms.
Canada - recruitingNA
A SMART Design to Optimize the Delivery of TEMPO for Men With Prostate Cancer and Their Caregivers
This study looks at TEMPO, an online program for men with prostate cancer and their family caregivers. It aims to help them manage cancer challenges and anxiety. We want to find the best way to offer TEMPO to improve their health and well-being.
Canada - recruitingNA
Emotion Focused Family Therapy for Parents of Children With Mental Health Difficulties
This study looks at a therapy called Emotion Focused Family Therapy (EFFT) for parents. It aims to teach parents skills to help their children aged 7-15 who are struggling with anxiety, depression, or behaviour issues. The hope is to improve how children feel and how families work together.
Canada - recruitingNA
Cognitive Remediation in Forensic Mental Health Care
This study looks at a special kind of mental exercise called 'cognitive remediation' for people in forensic mental health care. It aims to see if these exercises can improve thinking skills, everyday abilities, and mental well-being in patients dealing with conditions like schizophrenia or ADHD.
Canada - recruitingNA
Improving Care and Mental Well-Being for Adults With Heart Failure
This study looks at a new way to support people with heart failure by focusing on their mental health. It's called FRAME. The aim is to see if this support can be easily offered in different healthcare settings and to improve well-being for those with heart failure.
Canada - recruitingNA
JoyPop Mobile Mental Health App With Youth
This study looks at how a mental health app, JoyPop, can help young people (aged 12-17) who are waiting for mental health services. It aims to see if the app can improve how they manage their feelings while they wait for help.
Canada - recruiting
Biobank and Brain Health in Bordeaux.
This study, called "B cube," looks at how our brains change as we get older, especially from age 55. Researchers want to understand why some people's memories and thinking skills decline and how to prevent it. They are studying 2000 people in Bordeaux, France, focusing on things like diet and overall health.
France - not yet recruitingNA
Single Arm, Monocentric, Pilot Feasibility Study on an Interactive Virtual Reality Program in 20 Complex In-clinic Palliative Care Patients
This study is testing a new interactive virtual reality program called ZenctuaryVR+ for people receiving palliative care. It aims to see if using VR can help reduce symptoms like pain and anxiety by distracting the brain, especially for those with severe symptoms.
France - recruitingNA
The Sleep Course: An Online Sleep Intervention for Adults With Self-reported Sleep Difficulties
This study looks at an online course called 'The Sleep Course' for adults in Saskatchewan struggling with difficulties sleeping. It aims to see if this online therapy, which helps with sleep, depression, and anxiety, is effective and easy to use in real-world settings.
Canada - recruitingNA
TrueBlue Clinical Study - Investigating the Use of a Mobile Phone App TrueBlue for Monitoring Depression and Anxiety
This study is looking at a mobile phone app called TrueBlue. It aims to see if the app can safely and helpfully monitor feelings of depression and anxiety in pregnant women and new mothers in Nottinghamshire. We want to find out how easy it is to use and if it works well.
United Kingdom