- ongoing, recruitingTherapeutic confirmatory (Phase III)
MiBlock - Botulinum toxin type A blockade of the sphenopalatine ganglion in treatment-refractory chronic migraine
This study, called MiBlock, is looking into a new way to treat chronic migraine using an injection near a nerve in the face. It aims to see if this treatment can reduce the number of headache days compared to a dummy treatment, for people whose migraines haven't responded to other treatments.
Norway - recruitingPHASE3
A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years
This study is testing a new tablet called atogepant to see if it can help prevent chronic migraines in young people aged 12 to 17. We want to know if it's safe and if it works better than a dummy pill.
United States · Canada · Denmark - ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of Erenumab in Children (6 to < 12 Years) and Adolescents (12 to < 18 Years) With Chronic Migraine (OASIS PEDIATRIC [CM])
This study is testing a new medicine, Erenumab, for children and teenagers aged 6 to 17 who get chronic migraines. It wants to see if the medicine can reduce how often and how severe their migraines are, compared to a dummy medicine.
Italy · Germany · Hungary - recruitingPHASE3
A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine
This study is testing a new injection, Xeomin, for people with frequent migraines. We want to see if it reduces the number of migraine days compared to a dummy injection (placebo). It involves head and neck injections and lasts about a year.
United States · Austria · Canada - active not recruitingPHASE3
A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults
This study is testing a medicine called Dysport® for people who get chronic migraines. It aims to see if Dysport® can reduce how often and how bad migraines are, and if it's safe to use, compared to a dummy medicine.
United States · Canada · Czechia - recruitingPHASE2
A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults
This study looks into a new medicine called IPN10200, given as injections, to see if it can prevent migraine headaches in adults. It will check if the treatment is safe and how well it works for people who get migraines often.
United States · Australia · Brazil - recruitingPHASE2
Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial
This study looks at a cannabis-based medicine for teenagers (14-17) with ongoing severe headaches. We want to see if it's safe and if people can take it without too many side effects. It's happening in Canada over several months.
Canada - ongoing, recruitingTherapeutic confirmatory (Phase III)
Interventional, randomized, double-blind, parallel-group, placebo-controlled study to evaluate efficacy and safety of eptinezumab for the preventive treatment of migraine
This study looks at a new medicine called VYEPTI for people with long-lasting migraine. It compares VYEPTI to a dummy treatment to see if it reduces migraine days and is safe. The main goal is to find out how much VYEPTI can lower the number of migraine days over 12 weeks.
Poland · Slovakia · Spain