Adult Congenital Heart Disease research hub
11 indexed studies · 9 currently recruiting
- recruiting
Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry
This international study looks at how a type of medicine called SGLT2 inhibitors is used in adults with heart problems they were born with. Researchers want to see how safe these medicines are, if people tolerate them well, and if they help improve heart failure.
United States · Germany · Netherlands - not yet recruitingNA
Study of Exercise Capacity and Physical Activity in Children With Congenital Heart Disease
This study looks at how a special exercise plan can help children aged 5-18 with heart conditions to be more active. It aims to see if tailored activities can improve their fitness and overall well-being. It also considers what parents, teachers, and coaches think.
United Kingdom - not yet recruitingPHASE3
SGLT2 Inhibition With Empagliflozin in Fontan Circulatory Failure
This study is testing if a drug called empagliflozin can help adults with Fontan Circulatory Failure (FCF) feel better and improve their daily lives. FCF is a heart condition some people are born with.
Canada - recruiting
The PAtients pResenTing With COngenital HeaRt DIseAse Register (ARTORIA-R)
This study, called ARTORIA-R, is collecting information from many countries about adults with heart conditions they were born with (congenital heart disease) who need a heart transplant. It aims to understand why some need transplants and how they do afterwards.
Germany - recruitingNA
HIIT in Youth With Congenital Heart Disease (MedBIKE)
This study is looking at a home-based exercise program called MedBIKE for young people aged 10-18 with treated congenital heart disease. It aims to see if this special cycling program can improve how well they can exercise and their overall quality of life.
Canada - authorisedTherapeutic confirmatory (Phase III)
A prospective, open-label, non-randomized, multicentre trial to assess the safety and PD of Cangrelor as procedural platelet inhibitor in paediatric subjects from birth to <18 years of age undergoing diagnostic and/or therapeutic percutaneous vascular procedures for management of congenital heart disease
This study looks at a medicine called Cangrelor (Kengrexal) for children, from babies to teenagers, who are having heart procedures. It checks if the medicine is safe and how well it helps prevent blood clots during these procedures for congenital heart disease.
Germany · Portugal · Austria - recruitingNA
OPTImal Treatment of Sinus VENOSUS Defect
This study compares two ways to fix a heart problem called Sinus Venosus Defect (SVD): a new stent procedure and traditional surgery. It wants to see if the new stent is as safe and effective as surgery for adults.
France - not yet recruitingPHASE1, PHASE2
Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congenital Heart Disease Undergoing Surgical Repair
This study looks at how adjusting breathing machines could help children with heart problems after surgery. We're testing a special way to manage lung pressure to see if it makes their hearts and lungs work better.
Germany - recruiting
Effect of Fetal Aortic Valvuloplasty on Outcomes
This study looks at a procedure called fetal aortic balloon dilation for babies whose hearts aren't developing properly before birth. We want to see if this treatment helps prevent a severe heart condition called HLHS and improves their health outcomes while checking for any side effects.
United States · Austria · Canada - active not recruitingNA
The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical Study
This study is looking at a new heart valve called the Harmony TPV. It's for people with certain heart conditions, like when a heart valve doesn't close properly. The study wants to see how well this new valve works over a long time to help people feel better.
United States · Canada · Japan - recruitingNA
Digital Health Promotion for Children With Congenital Heart Disease and Their Guardians
This study looks at how a 12-week digital programme, using a special fitness tracker, can help children aged 8-13 with heart conditions and their parents. It aims to improve children's activity levels, health, and their family's well-being. We want to see if this technology can help them live healthier lives.
Germany