- active not recruiting
Minimal SN Tumor Burden
This study is gathering information on people with a certain type of melanoma to see if they can avoid a big surgery. We want to find out if removing fewer lymph nodes is safe for patients with very small amounts of cancer in their nodes.
Belgium · France · Germany - active not recruitingPHASE2
Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE)
This study looks at a new treatment called RP1, by itself and with another drug called nivolumab. It's for people with certain advanced cancers like lung cancer, some skin cancers, and specific solid tumours that haven't responded well to previous treatments.
United States · France · Germany - active not recruitingPHASE1
A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors
This study is testing a new drug, PF-08046049/SGN-BB228, for advanced melanoma and other difficult-to-treat solid cancers. It aims to find a safe dose and see how well it works, as well as checking for side effects.
United States · Canada · France - recruitingPHASE1, PHASE2
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
This study looks at a new drug, IDE196, for certain advanced cancers that have specific genetic changes called GNAQ/11 mutations or PRKC fusions. It checks if the drug is safe and effective alone or when combined with other existing cancer drugs.
United States · Australia · Canada - recruiting
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
This study looks at a new blood test to find cancer early in people who have already been treated for certain cancers. It aims to see if this test can tell when cancer might come back, helping doctors give the best care sooner.
United States · France · Germany - active not recruitingPHASE1
A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers
This study looks at a new drug, KFA115, on its own and with another drug, pembrolizumab, for various advanced cancers. It aims to find a safe and effective dose, helping doctors understand how these treatments work.
United States · Canada · China