Homozygous Familial Hypercholesterolemia (HoFH) research hub
5 indexed studies · 1 currently recruiting
- active not recruiting
Evaluation of the Effect of Lomitapide Treatment on Major Adverse Cardiovascular Events (MACE) in Patients With Homozygous Familial Hypercholesterolemia
This study looks at how a medicine called lomitapide affects people with a rare inherited condition called Homozygous Familial Hypercholesterolemia (HoFH). HoFH causes very high cholesterol. Researchers are checking if lomitapide helps reduce serious heart problems over time.
France · Greece · Italy - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase IIb, Multicenter, Randomized, Parallel-group, Double- blind, Placebo-controlled, Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AZD0780 in Participants with Dyslipidemia
This study looks at a new medicine called AZD0780 for people with high cholesterol. We want to see if it safely lowers bad cholesterol and other fats in the blood, which can help prevent heart problems. Participants will take the medicine or a dummy pill.
Denmark · Czechia · Spain - active not recruiting
Meta-Analyses of the Effect of Plant Protein Versus Animal Protein on Cardiometabolic Risk
This study looks at lots of past research to see if swapping animal protein for plant protein makes a difference to health conditions like diabetes, heart problems, and kidney issues. They want to understand if eating more plant-based protein, like from beans or nuts, can be better for our health.
Canada - active not recruitingNA
Pharmacist Case Finding and Intervention for Vascular Prevention Trial
This study looks at how pharmacists can help people lower their risk of heart disease. Heart disease is very common, and pharmacists often see patients. They might be able to help you understand and reduce your personal risk factors for heart problems.
Canada - not yet recruitingNA
SCORE! Non-Physician Health Worker (NPHW) Implementation Protocol (SIP)
This study helps people in the SCORE! Cohort with high blood pressure, unhealthy cholesterol, or blood sugar issues. We're using trained health workers, not doctors, to support better health through lifestyle advice and check-ups over 12 months.
Canada