Depression in Adolescence research hub
11 indexed studies · 5 currently recruiting
- not yet recruitingNA
Fluoxetine and Understanding Social Experiences
This study looks at how the antidepressant fluoxetine (Prozac) affects how young people aged 18-24 make social decisions. We want to understand how it impacts emotions, social interactions, and motivation. This helps us learn more about how antidepressants work in young adults.
United Kingdom - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study to evaluate the effect of multiple doses of carbamazepine on how long aticaprant (JNJ-67953964) stays in the body (pharmacokinetics) in healthy adults
This study looks at how a drug called aticaprant (JNJ-67953964) moves through the body and how long it stays there when healthy adults also take another drug, carbamazepine. It helps us understand how these medicines might interact.
Belgium - recruitingPHASE1
Phase 1 Study of ADX-626 in Healthy Participants
This study is looking for healthy adults aged 18-45 to test a new medicine called ADX-626. It's the very first time this medicine will be given to people. We want to see if it's safe and how it works in the body.
United Kingdom - ongoing, recruitingHuman Pharmacology (Phase I)- Other
An Open-label, Single-dose Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of Aticaprant (JNJ-67953964)
This study looks at how a new medicine, Aticaprant, is processed by the body in healthy adults. It's a very early stage of research, making sure the medicine works as it should.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
An Open-label, Single-dose, Parallel-group Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Aticaprant (JNJ-67953964)
This study is looking at how a new medicine, called Aticaprant, behaves in the body of healthy adults. Researchers want to see if having liver problems changes how the body handles this medicine, and if it's safe to use.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy volunteers to find out how long aticaprant stays in and acts on the body when administered with or without rabeprazole.
This study looks at a new medicine called aticaprant in healthy people. We want to see how long it stays in the body and how it works, both on its own and when taken with another medicine called rabeprazole.
Belgium - not yet recruitingPHASE2, PHASE3
Yeast Protein for Muscle Mass
This study compares yeast protein to whey protein for building muscle in healthy adults aged 18-35. Participants will do resistance training and take either yeast or whey protein daily for 16 weeks to see which is more effective. This trial aims to find a sustainable way to help people gain muscle.
Canada - ongoing, recruitingHuman Pharmacology (Phase I)- Other
An Open-Label, Single-Center, Single-Dose Study to Assess the Absolute Oral Bioavailability and Pharmacokinetics of Aticaprant Administered as an Oral Tablet and an Intravenous Infusion Microdose of 14C-Aticaprant in Healthy Participants
This study is looking at how a new drug, Aticaprant, is absorbed by the body. Researchers want to compare how well it enters the bloodstream when taken as a tablet versus a very small amount given directly into a vein. This helps them understand the best way to give the medicine.
Belgium - recruitingPHASE1
Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of ALXN2230 in Healthy Participants
This study is looking at a new medicine called ALXN2230 in healthy adults. We want to see if it's safe, how well the body handles it, and how it moves through the body. This is a very early stage of testing.
United Kingdom - recruitingPHASE1, PHASE2
RIG 101 Trial in Healthy Adults and Adults With Asthma
This study is testing a new medicine, RIG-101, for asthma attacks triggered by colds. We want to see if it's safe, and if it helps people with asthma and healthy volunteers. It combines early safety checks with later tests of how well it works.
United Kingdom - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study in healthy volunteers to find out how long aticaprant stays in and acts on the body when administered with or without food and with or without fluconazole
This study is looking at how a new medicine, called aticaprant, works in healthy people. We want to find out how long it stays in the body, and if food or another common medicine (fluconazole) changes how it works.
Belgium