Cardiometabolic Health research hub
21 indexed studies · 17 currently recruiting
- recruiting
Cardiometabolic Health in First Time Pregnancy
This study looks at how pregnancy complications like high blood pressure can affect a woman's heart health and risk of diabetes later on. It aims to understand these links better and find ways to prevent future problems.
United Kingdom - recruitingPHASE2
Transition to KPL-387 Monotherapy Dosing & Administration Study
This study looks at how people with recurrent pericarditis can safely switch from their usual medicines to a new drug called KPL-387. It checks if the new drug works well and if patients experience any side effects.
United States · Canada · France - recruiting
Abbott Structural Heart Device Registry
This study looks at how well Abbott heart devices work in day-to-day hospital care. It helps make sure these devices are safe and effective for people with different heart conditions, like holes in the heart or valve problems, as they are used in real life.
United States · Denmark · Estonia - recruitingNA
Therapy to Maintain Remission in Dilated Cardiomyopathy
This study looks at whether people with a recovered heart condition can safely stop some of their medication without their heart problems returning. It focuses on two specific types of heart failure medicines.
United Kingdom - recruitingNA
A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
This study compares two ways to plan heart artery procedures for people with hardened arteries. It uses advanced CT scans versus a standard internal ultrasound to see which method helps doctors work better and get similar good results for patients.
United States · Spain · United Kingdom - recruitingPHASE3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
This study looks at a new drug, acoramidis, for people who have a faulty gene that can cause a condition called ATTR. It aims to see if the drug can stop or slow down the disease from developing in people who don't yet have symptoms.
United States · Argentina · Australia - recruitingPHASE4
NT-proBNP Selected Prevention of Cardiac Events in Diabetic Patients
This study looks at how high doses of certain heart medicines (RAS-antagonists and beta-blockers) might help prevent heart problems in people with Type 2 diabetes who haven't had heart disease before. It also checks a blood marker called NT-proBNP.
Austria · Netherlands · New Zealand - recruitingNA
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
This study looks at two types of heart bypass surgery for women: using one or multiple healthy arteries. Researchers want to see if using more arteries leads to better long-term health, quality of life, and fewer future heart problems for women.
United States · Australia · Austria - recruitingNA
Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
This study is testing a new smartphone device called AliveCor 12-lead ECG. It aims to see if this device can accurately detect heart attacks (STEMI and NSTEMI) in people with chest pain, just as well as the standard ECG machines used in hospitals.
United States · United Kingdom - active not recruiting
Future Innovations in Novel Detection for Atrial Fibrillation (FIND-AF): Pilot Study
This study is testing a new way to find an irregular heartbeat called atrial fibrillation (AF) earlier. It uses a special computer tool and remote heart monitoring for people at higher risk. The goal is to see if this helps detect AF more often and leads to better treatment to prevent strokes.
United Kingdom - active not recruiting
Real-world Study on Dapagliflozin Usage in Patients With Heart Failure (HF) in Germany
This study looks at how a medicine called dapagliflozin is used for heart failure in Germany. Researchers want to understand how it affects people's symptoms, quality of life, and healthcare needs in everyday situations.
Germany - active not recruitingNA
Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD
This study looks at a new device, the reSept ASD Occluder, for treating a common heart condition called secundum Atrial Septal Defect (ASD). It aims to see if the device is safe and works well to close the hole in the heart.
United States · Canada · France - recruiting
Registry for the Improvement of Postoperative OutcomeS in Cardiac and Thoracic surgEry
This study looks at people having heart or chest surgery. We collect information before and during surgery to understand why some people have problems afterwards, like needing more care or developing complications. The goal is to improve care and make surgery safer for everyone.
France - recruiting
Mayo AVC Registry and Biobank
This study aims to better understand a heart condition called Arrhythmogenic Ventricular Cardiomyopathy (AVC) that can lead to sudden cardiac arrest. Researchers hope to find new genetic causes and ways to predict the disease, helping to save lives in affected families.
United States · United Kingdom - recruitingNA
Personalized Responses to Dietary Composition Trial 3
This study, PREDICT 3, aims to understand how different foods affect individuals. By looking at how people respond to meals in their everyday life, it helps create more personalised eating advice to improve health for conditions like diabetes and heart problems.
United States · United Kingdom - recruiting
Registry to Assess the Safety and Feasibility of the Subpulmonary Support with the Novel Venous Cannula in Patients with Failing/Absence of the Right Heart
This study looks at how well a special device, called an EXCOR Venous Cannula, works in supporting hearts that are struggling. It aims to make sure the device is safe and helps patients get better, both in the short and long term.
Germany - recruitingNA
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
This study looks at a new device, the Carillon Mitral Contour System, for people with heart failure caused by a leaky heart valve. It aims to see if the device is safe and helps improve their condition, comparing it to usual care without the device.
United States · Canada · France - recruiting
ACCESS Registry: A Post Market Follow-up Study to Monitor the Safety, Performance and Usability of Occlutech Accessory Medical Devices
This study looks at how safe and effective certain tools are when doctors fix heart problems with a small tube (catheter). It collects information from doctors using Occlutech medical devices during these procedures to make sure they work well.
Germany · Turkey (Türkiye) - enrolling by invitation
Global Utilization And Registry Database for Improved heArt preservatioN
This study looks at how well heart transplants work when donor hearts are carried in a special system called SherpaPak CTS. Researchers will compare outcomes of patients who received hearts using this system to those who received hearts transported in the old way, aiming for better heart preservation.
United States · Austria · Spain - recruitingNA
Randomization of Single vs Multiple Arterial Grafts
This study compares using one main artery graft to two or more in heart bypass surgery. It aims to see if using more grafts improves survival, reduces heart attacks, strokes, or the need for more procedures for people with coronary artery disease.
United States · Austria · Brazil - active not recruitingNA
The PulsePoint Study
This study looks at whether the PulsePoint app helps people near a sudden heart attack (cardiac arrest) in public places give CPR or use a defibrillator sooner. Half of these emergencies will get an app alert, and half won't, to see which approach works best.
United States · Canada