- authorisedTherapeutic use (Phase IV)
Intranasal nafarelin compared to subcutaneous triptorelin for triggering final oocyte maturation in ovarian stimulation: a non-inferiority randomised controlled clinical trial
This study compares two common fertility medications, Synarel nasal spray and daily Decapeptyl injections, to see which is better at helping eggs mature. It focuses on women undergoing fertility treatment for infertility, checking how many mature eggs are collected and looking at side effects and costs.
Spain - authorisedTherapeutic use (Phase IV)
Luteal phase support following letrozole treatment in women undergoing intrauterine insemination: a multicenter randomized trial
This study looks at a vaginal progesterone medication (Cyclogest) after fertility treatment (letrozole and IUI) to see if it helps women get pregnant and have healthy babies. It's for women experiencing infertility.
Denmark - ongoing, recruitingTherapeutic use (Phase IV)
The impact of the intensity of ovarian stimulation on embryo quality in predicted suboptimal responders. A randomized controlled trial.
This study looks at different ways to give fertility medicines to women who might find it harder to get pregnant. We want to see if changing the amount of medicine helps create better-quality embryos, which could improve chances of pregnancy.
Spain - authorisedTherapeutic use (Phase IV)
Exogenous progesterone as ovulation trigger – a pilot study
This study is looking into using a medicine called progesterone to help eggs mature for women having fertility treatment. It wants to see if this method works well and how it affects hormone levels, as a different way to encourage egg development.
Portugal - recruitingNA
Automation of Oocyte and Embryo Vitrification
This study compares a new automatic freezing method for eggs and embryos with the usual hand-freezing method. It aims to see if the new automated system works just as well. This could make fertility treatments more consistent and accessible for people hoping to start a family.
United Kingdom - ongoing, recruitingTherapeutic confirmatory (Phase III)
A randomized controlled trial comparing sequential of two shots of CFA vs CFA + rFSH for Elective Fertility Preservation. The 2-shot protocol.
This study looks at a new way to help women preserve their fertility. Researchers are comparing two different methods for stimulating the ovaries to collect eggs, using a combination of hormone medications. The goal is to find the best way to collect healthy eggs for future use.
Spain - recruitingNA
Pesticides and Infertility: Oxidative Stress Via Circulating Cell-free DNA and Gut/Genital Microbiome Signatures in Women With Endometriosis
This study looks into how pesticides might affect women with endometriosis, especially regarding fertility. Researchers are exploring how gut and vaginal germs, along with tiny bits of DNA, could be linked to the condition and exposure to chemicals.
France - recruitingNA
Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities
This study is looking at new genetic tests to better understand why some people experience infertility, learning difficulties, birth defects, or miscarriages. It compares these newer, more detailed tests to older ones, hoping to find better ways to spot problems with chromosomes.
France - recruiting
Impact of a Predetermined Day 5 ET vs. a Predetermined Day 6 ET on Clinical Pregnancy Rate After ICSI Treatment
This study looks at whether transferring an embryo on day 6 after IVF treatment is as effective as transferring it on day 5. It hopes to help people experiencing infertility by improving treatment options and pregnancy chances.
Germany - recruiting
Clinical Cohort Study on the Endocrinology and Vaginal/Endometrial Microbiome of the Luteal Phase in Assisted Reproduction
This study looks at hormones and tiny germs to understand how pregnancy continues after IVF. Researchers want to find out when the placenta takes over hormone production and if vaginal germs affect pregnancy success after frozen embryo transfer.
Germany - not yet recruiting
Plasma Relaxin Measurement Based on Endometrial Preparation for Embryo Transfer
This study looks into why pregnancies after IVF might have more problems than natural ones. It focuses on a hormone called relaxin, which could help explain why certain IVF methods lead to different outcomes for mums and babies, especially in the first trimester.
France - recruiting
Effects of Infertility and Assisted Reproductive Technology on Sexual Function and Behavior
This study looks at how infertility and fertility treatments might affect women's sex lives. Researchers want to understand if these experiences change sexual desire, satisfaction, or activity. The aim is to help doctors better support women's overall well-being during fertility care.
Canada - not yet recruiting
Impact of Uterine Immune Profiling and Personalized Treatments in Patients Receiving a Single Blastocyst: a Matched Controlled Study
This study looks at how checking a woman’s womb carefully before IVF or similar treatments affects her chances of having a baby. It compares women who had this check with those who didn't, to see if it makes a difference to successful pregnancies.
France - not yet recruiting
The Impact of Having a Tattoo on Fertility Treatment Outcome
Researchers are studying if tattoos affect how well IVF fertility treatments work. They want to see if having tattoos, their size, how long you've had them, or the ink used, changes your chances of becoming pregnant after IVF.
Canada - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Phase 1, open label, randomized, 2-sequence, 2-period, crossover, single center study to evaluate the pharmacokinetics of follitropin alfa from 2 manufacturing processes, administered as a single subcutaneous 450 IU dose to pituitary-suppressed healthy premenopausal female participants.
This study is looking at how a fertility medicine (follitropin alfa) is handled by the body. It compares two versions of the medicine in healthy women to understand how they work. This information helps us learn more about potential treatments for infertility.
Netherlands