- recruitingPHASE1
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
This study is testing a new drug, NXP900, for people with advanced cancers like lung cancer or kidney cancer. It's a very early-stage trial to see if the drug is safe and what dose works best.
United States · United Kingdom - not yet recruitingPHASE2
SELECTmeso A Trial for Patients With Relapsed Malignant Mesothelioma SELECTmeso1 A Trial of BMS-986504 in Patients With MTAP-deficient Relapsed Mesothelioma
This study, called SELECTmeso, looks for new treatments for a type of cancer called mesothelioma. It checks your tumour for specific markers and then offers a treatment that might work best. The first part, SELECTmeso1, tests a drug called BMS-986504 for tumours with an MTAP deficiency.
United Kingdom - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Pembrolizumab plus autologous dendritic cell vaccine in patients with advanced mesothelioma who have failed prior therapies
This early-stage study is testing a new treatment for advanced mesothelioma that hasn't responded to previous therapies. It combines a drug called pembrolizumab with a special vaccine made from a patient's own cells.
Italy - active not recruitingPHASE1
A Phase I Study of IAG933 in Patients With Advanced Mesothelioma and Other Solid Tumors
This study is testing a new drug, IAG933, for people with advanced mesothelioma and certain other cancers. It aims to find a safe dose and see how well it works when standard treatments haven't helped or aren't suitable.
United States · Australia · Canada - recruitingNA
EXTRA-Meso (EXercise TheRApy in Mesothelioma) Feasibility
This study looks at whether it's possible to run an exercise programme for people with mesothelioma. It wants to see if people will join and keep going with the programme, and what helps or stops them from doing so. It will help design better studies in the future.
United Kingdom - active not recruitingPHASE1, PHASE2
Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer
This study is testing a new cell therapy called gavo-cel for advanced cancers like mesothelioma and ovarian cancer. It explores how well gavo-cel works, both alone and with other cancer drugs, in people whose tumours produce a specific protein called mesothelin.
United States · Canada - active not recruitingPHASE1
A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors
This study is testing a new drug, PF-08046049/SGN-BB228, for advanced melanoma and other difficult-to-treat solid cancers. It aims to find a safe dose and see how well it works, as well as checking for side effects.
United States · Canada · France - active not recruitingPHASE1
A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers
This study looks at a new drug, KFA115, on its own and with another drug, pembrolizumab, for various advanced cancers. It aims to find a safe and effective dose, helping doctors understand how these treatments work.
United States · Canada · China