- ongoing, recruitingTherapeutic exploratory (Phase II)
Ticagrelor monotherapy after coronary stenting in patients with acute myocardial infarction - A prospective single-centre, single-arm phase II study
This study looks at people who've had a heart attack and a stent fitted. Researchers are testing a drug called Brilique to see if it can prevent further heart problems like another heart attack or blood clots in the stent, within three months.
Sweden - recruiting
Barts Sex-CAD Database - Sex Hormones and Inflammatory Status in Coronary Artery Disease
This study looks at how hormones and inflammation affect heart artery disease in men and women, especially for women after menopause. Researchers at Barts Heart Centre hope to find better ways to treat heart conditions by understanding these differences.
United Kingdom - recruiting
Non-invasive Coronary Thrombus Imaging to Define These Cause of Acute Myocardial Infarction
This study looks into a new scan that can detect blood clots in heart arteries after a heart attack. It aims to help doctors better understand what causes heart attacks and make sure patients get the right treatment.
United Kingdom - recruitingNA
Trans-coronary Cooling and Dilution for Cardioprotection During Revascularisation for ST-elevation Myocardial Infarction
This study is looking at a new way to protect the heart during a heart attack. We're testing if gently cooling the heart directly through a small tube, instead of the whole body, can reduce damage. This might make the current treatment even better.
United Kingdom - active not recruiting
Outcomes of Patients Who Survived Treatment on an Intensive Care Unit for COVID-19 in England and Wales
This study looks at the health of people in England and Wales one year after they left intensive care for COVID-19. Researchers will compare their health to people who were in intensive care for other reasons. The aim is to understand long-term health effects.
United Kingdom - recruiting
Early Discharge Pathway Registry
This study looks at people who had a heart attack and were discharged early from the hospital after a procedure called PCI. We want to understand their health and recovery better to improve care for future patients.
United Kingdom - recruitingNA
Sixth Generation High-sensitivity Cardiac Troponin T for the Early Rule Out of Myocardial Infarction: a Controlled Before and After Study
This study looks at a new, more accurate blood test for heart attacks. It aims to see if this new test helps doctors diagnose patients quicker, speeds up decisions about going home, and eases pressure on NHS emergency departments, all while keeping patients safe.
United Kingdom - recruitingNA
Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator Implantation
This study looks at whether a small device, called a defibrillator, is still the best way to prevent sudden death in people who have had a heart attack and have a weakened heart. We want to see if modern medicines alone are just as good.
Austria · Belgium · Czechia - active not recruiting
Heart Attack Research Program- Imaging Study
This study looks at people who've had a heart attack but don't have blockages in their main heart arteries. Researchers use special scans to understand why this happens and track their health for up to 10 years.
United States · Canada · United Kingdom - recruiting
Establishing the Incidence of Tako-tsubo Cardiomyopathy in Scotland
This study in Scotland looks at a heart condition called Takotsubo cardiomyopathy, which acts like a heart attack but isn't. Researchers are finding out how many people have it, what causes it, and how they recover, comparing them to people who've had heart attacks and healthy individuals.
United Kingdom - recruitingNA
Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
This study is testing a new smartphone device called AliveCor 12-lead ECG. It aims to see if this device can accurately detect heart attacks (STEMI and NSTEMI) in people with chest pain, just as well as the standard ECG machines used in hospitals.
United States · United Kingdom - active not recruiting
Residual Inflammation and Plaque Progression Long-term Evaluation
This study looks at how inflammation in blood vessels after a heart attack might lead to future problems. We use special scans to see inflammation and track changes in blood vessels over time. The goal is to understand how to better prevent future heart issues.
United Kingdom - recruiting
Lipid Testing After Myocardial Infarction at the Montreal Heart Institute
This study at the Montreal Heart Institute looks at cholesterol levels in people after a heart attack. Doctors want to know if measuring cholesterol right after a heart attack or a couple of days later gives different results, to help decide the best treatment.
Canada - recruitingNA
Lymphatic Organs and Myocardium After Myocardial Infarction
This study looks at how your body's defence system reacts after a heart attack. We use special scans to see if changes in certain body parts, like tiny glands, can tell us how your heart will recover over time.
Germany - recruiting
Biomarkers in Acute Cardiac Care
Researchers are studying new ways to diagnose heart attacks better and find out what causes chest pain. They're looking at different markers in the body and factors like lifestyle to improve how we understand and treat heart problems.
Germany - recruitingNA
Cohort of STEMI Patients 2
This study looks at how heart attacks (STEMI) affect people. Researchers want to understand better why they happen, how treatments work, and how people's lives change afterwards. They hope to find new ways to help people who have had a heart attack.
France - not yet recruitingNA
Digital MEDIcal TWIN for the Prediction of Arrhythmic Sudden Cardiac Death After a Myocardial Infarction
This study aims to find a better way to predict who might be at risk of sudden cardiac arrest after a heart attack. Currently, we use a measurement called LVEF, but it's not perfect. This research looks at new methods to improve this prediction.
France - recruiting
Cardio-Renal Registry
This study is looking at patients with kidney disease heart problems. It aims to understand why heart issues are common in people with kidney conditions and how best to treat them. We hope to improve care for these patients.
United Kingdom - active not recruiting
Impact of Peripheral Vascular Stiffness Assessment on Risk Prediction in Patients With Myocardial Infarction
This study looks at people who have had a heart attack to see how stiff their blood vessels are. We want to find out if this stiffness helps predict future heart problems, especially a type of heart failure, and improve how we look after patients.
France - recruiting
Carotid Intraplaque Neovascularization Combined With Stress Echo
This study looks at a new way to predict heart attacks and strokes. It combines a standard heart stress test with a special neck ultrasound. This aims to find people at higher risk whose usual tests might miss them, by looking closely at fatty build-ups in blood vessels.
Canada - recruitingNA
Development of Novel Physiological CMR Methods in Health and Disease
This study uses special MRI scans to understand how the heart works in healthy people and those with heart conditions. It looks at how the heart responds to small challenges, like a fluid boost, to find better ways to spot and treat heart problems.
United Kingdom - recruitingNA
The Next Leap in Cardiac Magnetic Resonance Imaging:Cycling the Field
This study is developing a new, improved MRI scanner to get more detailed pictures of the heart. Researchers want to see if this new technology can spot differences in heart tissue after a heart attack, helping us understand heart health better.
United Kingdom - recruiting
Barts-MINOCA Registry
This study looks at heart attack patients in the UK who have clear arteries (MINOCA). Researchers are studying their health over time using existing information to learn more about this condition and how best to care for it. No new tests are involved.
United Kingdom - recruitingNA
Cohort Study - SBRT for VT Radioablation
This study is looking at a new way to treat a fast and irregular heartbeat called ventricular tachycardia (VT). It uses a type of precise radiation, usually for cancer, to fix the 'short circuit' in the heart for people who haven't responded to usual treatments.
Canada - recruiting
Barts Revascularisation Registry
This study looks at heart disease (myocardial infarction and angina) and how different treatments, like procedures to open blocked arteries, affect patients. It uses existing information from a large heart centre to learn more about these conditions and improve care.
United Kingdom