squamous cell carcinoma of the head and neck research hub
7 indexed studies · 5 currently recruiting
- ongoing, recruitingTherapeutic exploratory (Phase II)
Activity and safety of peptide-based immunotherapy in an umbrella window of opportunity phase II study in patients with squamous cell carcinoma of the head and neck.
This study is looking at new treatments for head and neck cancer. It tests three different approaches using special vaccines (IO103, IO102, or both) to see how safe and effective they are. The aim is to help the body's immune system fight the cancer.
Belgium - recruitingPHASE1, PHASE2
Modi-1 Moditope in Breast, Head and Neck, Ovarian, or Renal Cancer
This study is testing a new vaccine called Modi-1 Moditope for advanced cancers like breast, head and neck, ovarian, or kidney cancer. It aims to see if it's safe, and if it can help the body fight cancer, alone or with other treatments.
United Kingdom - recruitingPHASE1
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
This study is testing a new drug, PF-08046054/SGN-PDL1V, alone and with an existing medicine called pembrolizumab, for various advanced cancers. Researchers want to see how safe it is and if it has any effect on the cancer. It's a very early stage study.
United States · Belgium · Canada - recruiting
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
This study looks at a new blood test to find cancer early in people who have already been treated for certain cancers. It aims to see if this test can tell when cancer might come back, helping doctors give the best care sooner.
United States · France · Germany - active not recruitingPHASE3
Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer
This study looks at a new drug, Monalizumab, combined with Cetuximab, for people with head and neck cancer that has come back or spread. It compares this combination to Cetuximab with a dummy drug (placebo) to see if it's safe and effective.
United States · Argentina · Australia - not yet recruiting
Cisplatin-induced Cochlear and Vestibular Damage in Head and Neck Cancer
This study looks at how a cancer drug called cisplatin can affect hearing and balance in people with head and neck cancer. We aim to find better ways to check for these side effects and understand why they happen, especially by comparing patients receiving cisplatin with those who don't.
Germany - not yet recruitingPHASE2
Intratumoral Gemcitabine, Paclitaxel, Carboplatine and Intravenous Nivolumab for Locally Recurrence of Head and Neck Cancers
This study looks at a new way to treat head and neck cancer that has come back after other treatments. It combines injecting medicines directly into the tumor with an existing immunotherapy treatment (Nivolumab) to see if this combination works better.
France