- Active not recruitingPHASE3
A Phase III Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES)
This study looks at a new drug called benralizumab for Hypereosinophilic Syndrome (HES) in people aged 12 and over. It compares benralizumab to a dummy drug to see if it's safe and helps reduce HES symptoms.
For: Hypereosinophilic SyndromeUnited States · Argentina · Austria - RecruitingPHASE3
Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment
This study looks at a new treatment called benralizumab for people with severe asthma. It compares adding benralizumab to your usual asthma inhaler with just increasing the dose of your inhaler. We want to see if benralizumab helps control asthma better and is safe.
For: Eosinophilic AsthmaUnited States · Bulgaria · Canada - Active not recruitingPHASE3
Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab.
This study compares two treatments, benralizumab and mepolizumab, for a rare condition called Eosinophilic Granulomatosis with Polyangiitis (EGPA). Researchers want to see which one works better and is safer for people whose EGPA keeps coming back or isn't well controlled, even with other medicines.
For: Eosinophilic Granulomatous VasculitisUnited States · Belgium · Canada - RecruitingPHASE3
A Trial to Investigate Benralizumab in Children With Eosinophilic Diseases
This study is looking into a medicine called benralizumab for children aged 6 to 17 with rare blood conditions called EGPA or HES. We want to see if it's safe, how well it works, and how the body handles it over time.
For: Eosinophilic Granulomatosis With Polyangiitis (EGPA) · Hypereosinophilia Syndrome (HES)United States · Brazil · Canada - Active not recruitingPHASE4
Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics
This study looks at how a medicine called benralizumab affects the lungs of people with severe asthma. It aims to see if the treatment can improve lung structure and how well the lungs work in people whose asthma isn't controlled by usual medicines.
For: AsthmaUnited States · Canada · Denmark - RecruitingPHASE3
A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)
This study looks at a new medicine called benralizumab for children aged 6 to 18 with severe asthma. It wants to see if the medicine can stop asthma attacks and if it's safe. Half the children get the medicine, and half get a dummy medicine.
For: AsthmaUnited States · Argentina · Canada